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T80697β5i-IN-1;化合物 β5i-IN-1β5i-IN-1
β5i-IN-1 is a selective inhibitor of β5i, exhibiting potent activity with an IC50 of 8.463 nM. It modulates immune responses by promoting the release of TNF-α and IL-6 and affecting NF-κB transcriptional activity. This compound has applications in the research of idiopathic pulmonary fibrosis [1].
价 格:¥电议型 号:T80697产 地:中国大陆
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T80691β-Herpesvirus protease-IN-1;化合物 β-Herpesvirus protease-IN-1β-Herpesvirus protease-IN-1
β-Herpesvirus protease-IN-1 (compound 19) serves as an inhibitor of β-herpesvirus protease, exhibiting IC50 values of 2.5 μM for HCMVPro and 0.33 μM for HHV6Pro [1].
价 格:¥电议型 号:T80691产 地:中国大陆
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T80644DNA polymerase-IN-1;DNA polymerase 抑制剂1DNA polymerase-IN-1
DNA polymerase-IN-1, a DNA polymerase inhibitor, exhibited antiproliferative activity against tumor cells with a half-inhibitory concentration (IC50) of 20.7 μM. DNA polymerase-IN-1 inhibited Taq DNA polymerase with an IC50 of less than 250 μM. DNA polymerase-IN-1 was shown to inhibit Taq DNA polymerase by RT- DNA polymerase-IN-1 showed antiretroviral activity in vitro by RT-PCR assay and can be used to study oxidative damage and colorectal cancer.
价 格:¥电议型 号:T80644产 地:中国大陆
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T80640EBOV-IN-1;EBOV抑制剂1EBOV-IN-1
EBOV-IN-1 is an adamantane dipeptide piperazine inhibitor against Ebola virus (EBOV) that inhibits EBOV infection and suppresses pseudotypic EBOV infection.
价 格:¥电议型 号:T80640产 地:中国大陆
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T80626VGSCs-IN-1;VGSCs抑制剂1VGSCs-IN-1
VGSCs-IN-1 is a potent VGSC inhibitor, a 2-piperazine analog of Riluzole that exhibits good blocking activity on Nav1.4.VGSCs-IN-1 can be used to study cellular excitability disorders.
价 格:¥电议型 号:T80626产 地:中国大陆
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T80534Pterinotoxin-1;化合物 Pterinotoxin-1Pterinotoxin-1
Pterinotoxin-1 is a peptide toxin that functions as an inhibitor of sodium channels [1].
价 格:¥电议型 号:T80534产 地:中国大陆
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T80533Pterinotoxin-2;化合物 Pterinotoxin-2Pterinotoxin-2
Pterinotoxin-2 is a peptide toxin that acts as a sodium channel inhibitor [1].
价 格:¥电议型 号:T80533产 地:中国大陆
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T80492Mambalgin-2;化合物 Mambalgin-2Mamb-2;Mamb-2
Mambalgin-2 (Mamb-2), a venom peptide sourced from the African black mamba, acts as an inhibitor of acid-sensitive ion channels (ASICs). It is utilized in research focused on pain and neurological diseases [1].
价 格:¥电议型 号:T80492产 地:中国大陆
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T80452Ceratotoxin-1;化合物 Ceratotoxin-1CcoTx1|||β-TRTX-cm1a;CcoTx1|||β-TRTX-cm1a
Ceratotoxin-1 (CcoTx1) is a peptide toxin that functions as an inhibitor of various voltage-gated sodium channel subtypes. It selectively inhibits Nav1.1/β1, Nav1.2/β1, Nav1.4/β1, and Nav1.5/β1 with IC50 values of 523 nM, 3 nM, 888 nM, and 323 nM, respectively. Additionally, Ceratotoxin-1 is known to inhibit Nav1.8/β1 [1].
价 格:¥电议型 号:T80452产 地:中国大陆
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T80451Ceratotoxin-2;化合物 Ceratotoxin-2CcoTx2|||β-TRTX-cm1b;CcoTx2|||β-TRTX-cm1b
Ceratotoxin-2 (CcoTx2) is a voltage-gated sodium channel inhibitor, demonstrating half maximal inhibitory concentrations (IC50) of 8 nM for Na v 1.2/β 1 and 88 nM for Na v 1.3/β 1 [1].
价 格:¥电议型 号:T80451产 地:中国大陆
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T80435Heteropodatoxin-1;化合物 Heteropodatoxin-1Heteropodatoxin-1
Heteropodatoxin-1 (HpTx1), a spider peptide toxin, acts as an inhibitor of the Kv4.2 current, while concurrently inhibiting Nav1.7 and activating Nav1.9 channels. However, it has no effect on Nav1.8 channels [1].
价 格:¥电议型 号:T80435产 地:中国大陆
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T80434Heteropodatoxin-2;化合物 Heteropodatoxin-2Heteropodatoxin-2
Heteropodatoxin-2, a 30-amino acid peptide, inhibits the Kv4.2 current in Xenopus laevis oocytes through a voltage-dependent mechanism, exhibiting reduced blocking at more positive potentials [1].
价 格:¥电议型 号:T80434产 地:中国大陆
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T80190Waglerin-1;化合物 Waglerin-1Waglerin-1
Waglerin-1, a competitive antagonist of the muscle nicotinic acetylcholine receptor (nAChR), comprises 22 amino acids [1].
价 格:¥电议型 号:T80190产 地:中国大陆
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T80177Phlotoxin-1;化合物 Phlotoxin-1PhlTx1;PhlTx1
Phlotoxin-1 (PhlTx1), a 34-amino acid peptide featuring three disulfide bridges, is derived from the Phlogiellus genus spider and acts as an antinociceptive agent by inhibiting the NaV1.7 channel [1] [2].
价 格:¥电议型 号:T80177产 地:中国大陆
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T80061Hongotoxin-1;化合物 Hongotoxin-1Hongotoxin-1
Hongotoxin-1, a chemical compound isolated from the venom of Centruroides limbatus, functions as a potassium channel inhibitor. It exhibits inhibitory concentrations (IC50) for potassium channel subtypes Kv1.1, Kv1.2, Kv1.3, and Kv1.6 at 31 pM, 170 pM, 86 pM, and 6000 pM, respectively [1].
价 格:¥电议型 号:T80061产 地:中国大陆
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T80053Phrixotoxin-1;化合物 Phrixotoxin-1Phrixotoxin-1
Phrixotoxin 1, a specific peptide inhibitor of Kv4 potassium channels, originates from the venom of the theraphosid spider Phrixotrichus auratus [1] [2].
价 格:¥电议型 号:T80053产 地:中国大陆
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T79981Nitric oxide production-IN-1;化合物 Nitric oxide production-IN-1Nitric oxide production-IN-1
Nitric oxide production-IN-1 (Compound 1) is an inhibitor of nitric oxide (NO) production extracted from Tupistra chinensis. It effectively suppresses NO synthesis in rat abdominal macrophages upon stimulation with lipopolysaccharide [1].
价 格:¥电议型 号:T79981产 地:中国大陆
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T79945Ferroptosis-IN-1;化合物 Ferroptosis-IN-1Ferroptosis-IN-1
Ferroptosis-IN-1, a diterpene derived from A. campylantha, functions as a ferroptosis inhibitor with an EC50 of 10 μM and is utilized in the study of neuroinflammatory diseases [1].
价 格:¥电议型 号:T79945产 地:中国大陆
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T79917FAP-IN-2;化合物 FAP-IN-2FAP-IN-2
FAP-IN-2 is a 99mTc-labeled, isonitrile-containing derivative of a fibroblast activation protein (FAPI) inhibitor suitable for tumor imaging [1].
价 格:¥电议型 号:T79917产 地:中国大陆
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T79905Akt/ROCK-IN-1;化合物 Akt/ROCK-IN-1Akt/ROCK-IN-1
Akt/ROCK-IN-1 (B12) is a dual inhibitor targeting Akt and ROCK, exhibiting IC50 values of 0.023 nM and 1.47 nM, respectively. It possesses antitumor efficacy against neuroblastoma [1].
价 格:¥电议型 号:T79905产 地:中国大陆